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Anti-MLF1 Interacting Protein/PBIP1 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Centromere protein U |
Synonyms: | CENP U, CENP-50, CENP50, CENPU50, centromere protein of 50 kDa, HHV8 LNAIP1, ICEN24, KLIP1, LNAIP 1, KSHV LNAIP1, MLF1IP, MLF1IP1, PBIP1, Polo-box-interacting protein 1MLF1-interacting protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MLF1 Interacting Protein/PBIP1 |
Uniprot ID: | Q8C4M7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus, Chromosome |
Predicted MW. / Observed MW. | 46 kDa / 45 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | heart, kidney |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 900 | colon cancer, testis, colon, liver |
Background
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
Images
| Western blot analysis of KLIP1 (GB114849) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded human colon cancer using KLIP1 (GB114849) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded mouse Colon using KLIP1 (GB114849) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded mouse testis using KLIP1 (GB114849) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded rat testis using KLIP1 (GB114849) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded rat Colon using KLIP1 (GB114849) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded human liver using KLIP1 (GB114849) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |