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| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MNK1 rabbit polyclonal antibody |
Gene Name: | MAP kinase-interacting serine/threonine-protein kinase 1 |
Synonyms: | MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, MNk1, Mknk1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MNK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q9BUB5, O08605 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 1000-1: 3000 | brain, colon, liver cancer, lung cancer, ovarian cancer, tonsil |
Background
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G.
Images
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Immunohistochemistry of paraffin embedded human colon using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunohistochemistry of paraffin embedded human tonsil using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunofluorescence of paraffin embedded human liver cancer using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using MKNK1 (GB111286) at dilution of 1:1300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
