Reactivity: | M,R & M |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | 28S ribosomal protein S22, mitochondrial |
Synonyms: | MRP-S22, S22mt, Mrps22, Rpms22, C3orf5, COXPD5, GIBT, GK002 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MRPS22 |
Uniprot ID: | Q9CXW2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 kDa / 41 kDa |
Applications
WB | Mouse, Rat | 1: 500-1: 1000 | muscle, heart, liver |
ICC/IF | Mouse | 1: 50-1: 200 | NIH-3T3 |
Background
MRPS22, also named as C3orf5, RPMS22 and S22mt, is a component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. Defects in MRPS22 are the cause of combined oxidative phosphorylation deficiency type 5 (COXPD5). MRPS22 is a 360-amino-acid protein that has been found in a limited number of species, having no ortholog in fungi or prokaryotes. The exact location of MRPS22 in the three dimensional structure of the ribosome and its exact function are currently unknown.
Images
Western blot analysis of MRPS22 (GB111366) at dilution of 1: 500 |
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Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using MRPS22(GB111366) at dilution of 1: 50-1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |