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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MTAP rabbit polyclonal antibody |
Gene Name: | S-methyl-5'-thioadenosine phosphorylase |
Synonyms: | 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase, Mtap |
Immunogen: | Recombinant protein corresponding to Mouse MTAP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 31 kDa |
Observed MW. | 29 kDa |
Uniprot ID: | Q13126, Q9CQ65 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, kidney |
Background
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded MTAP protein is a 5-deoxy-5-methylthioadenosine (MTA) phosphorylase, converting MTA to salvageable intermediates including adenine and 5-methylthioribose-1-phosphate.The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted.
Images
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Western blot analysis of MTAP (GB111529) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
