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Anti-MUC1/CD227 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Mucin-1 |
Synonyms: | ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM, PEMT, Episialin, EAM, CA 15-3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CD227 |
Uniprot ID: | P15941 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 122/25 kDa / 25 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | lung, kidney, endometrial cancer, breast cancer |
Background
Mucin 1 (MUC1 [CD227]) is a type I membrane-tethered glycopro tein that is expressed on epithelial cells and extends far above the glycocalyx. MUC1 is overexpressed and aber rantly glycosylated in adenocarcinomas and in hematological malignancies. As a result, MUC1 has been a target for tumor immunotherapeutic studies in mice and in humans.MUC1 has been shown to have anti-adhesive and immunosuppressive properties, protects against infections, and is involved in the oncogenic process as well as in cell
Images
| Western blot analysis of CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat lung using CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat kidney using CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human kindey using CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using CD227 (GB114938) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using CD227 (GB114938) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human endometrial cancer using CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using CD227 (GB114938) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using CD227 (GB114938) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
