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Anti-Mast Cell Chymase Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Chymase |
Synonyms: | Alpha-chymase, Mast cell chymase 1, Mast cell chymase 5, mMCP-5, Mast cell protease I, Cma1, Mcpt5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Chymase |
Uniprot ID: | |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | skin, stomach |
Background
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.
Images
| Immunohistochemistry analysis of paraffin-embedded rat skin using Chymase (GB111085) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse skin using Chymase (GB111085) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse stomach using Chymase (GB111085) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
