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Anti-Midkine Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Midkine rabbit polyclonal |
Gene Name: | Midkine |
Synonyms: | ARAP, MDK, MK, MK1, NEGF2, Retanoic acid-responsive protein, Retinoic acid-induced differentiation factor, Neurite outgrowth-promoting factor 2 |
Immunogen: | Recombinant protein corresponding to Mouse Midkine |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 15 kDa |
Observed MW. | 15 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 300-1: 800 | pancreas |
Background
Midkine is a heparin-binding growth factor identified over 20 years ago and enhances the survival, migration and many other activities of target cells. Midkine is rich in both basic amino acids and cysteine, and is not related to most other growth factors/cytokines. It is strongly expressed during embryonic periods, especially at the midgestation stage, and plays important roles in development, especially in neurogenesis. Midkine expression in adult tissue is generally weak or undetectable, and it is induced upon injury and exerts many activities related to tissue repair. The biological activities of midkine in malignant tumors include proliferation, angiogenesis, invasion and metastasis. Various cancers express significantly higher levels of the midkine protein in early stage tumor tissues than in adjacent normal tissue.
Images
 | Western blot analysis of MDK (GB113537) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
