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Anti-Miner1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | CDGSH iron-sulfur domain-containing protein 2 |
Synonyms: | CDGSH iron sulfur domain 2, CDGSH2, CISD2, ERIS, Miner1, MitoNEET related 1 protein, NAF 1, WFS2, ZCD2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Miner1 |
Uniprot ID: | Q9CQB5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 15 kDa / 15 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 1000 | heart, kidney, brain |
Background
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Images
| Western blot analysis of CISD2 (GB114877) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
