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Anti-Mineralocorticoid receptor Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Mineralocorticoid receptor rabbit polyclonal antibody |
Gene Name: | Mineralocorticoid receptor |
Synonyms: | NR3C2, MCR, MLR, MR, NR3C2VIT, nuclear receptor subfamily 3 group C member 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 107 kDa |
Observed MW. | 107 kDa |
Uniprot ID: | Q8VII8, P08235 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Hela, HepG2, MCF7 |
Background
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Images
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Western blot analysis of MCR (GB11379) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
