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Anti-Mineralocorticoid receptor Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Mineralocorticoid receptor rabbit polyclonal antibody |
Gene Name: | Mineralocorticoid receptor |
Synonyms: | NR3C2, MCR, MLR, MR, NR3C2VIT, nuclear receptor subfamily 3 group C member 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q8VII8, P08235, P22199 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | brain, colon, colon cancer, heart |
Background
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Images
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Immunohistochemistry of paraffin embedded mouse colon using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat colon using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat heart using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded human colon cancer using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse colon using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
|
Immunofluorescence of paraffin embedded rat brain using MR (GB11379-1) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
