Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
Synonyms: | Adapter protein X11, Apba1, Neuron specific X11 protein, UROP11, X11alpha, x11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Mint-1 |
Uniprot ID: | B2RUJ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Rat | 1: 1000-1: 3000 | brain, spinal marrow |
Background
Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
Images
Immunohistochemistry analysis of paraffin embedded rat brain using APBA1 (GB114947) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat spinal marrow using APBA1 (GB114947) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |