Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MitoNEET rabbit polyclonal antibody |
Gene Name: | CDGSH iron-sulfur domain-containing protein 1 |
Synonyms: | MitoNEET, Cisd1, D10Ertd214e, Zcd1, C10orf70, MDS029, MGC14684, CDGSH-type domain 1 |
Immunogen: | Recombinant protein corresponding to Mouse MitoNEET |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 12 kDa |
Observed MW. | 12 kDa |
Uniprot ID: | Q91WS0, B0K020 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, skeletal muscle, liver |
Background
MitoNEET, also named CISD1, belongs to a previously uncharacterized ancient family of proteins for which the hallmark is the presence of a unique 39 amino acid CDGSH domain. It is a single-pass type III membrane protein, located in mitochondrion outer membrane and may play a role in regulating maximal capacity for electron transport and oxidative phosphorylation. MitoNEET is a recently identified drug target for a commonly prescribed diabetes drug, Pioglitazone.
Images
Western blot analysis of CISD1 (GB111537) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |