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Recombinant Anti-Myeloperoxidase Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Myeloperoxidase (MPO) (EC 1.11.2.2) [Cleaved into: Myeloperoxidase light chain; Myeloperoxidase heavy chain] |
Synonyms: | MPO, myeloperoxidase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MPO |
Uniprot ID: | P11247 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Subcellular location: | Lysosome |
Predicted MW. / Observed MW. | 84 kDa / 60 kDa |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | spleen, lung |
Background
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Images
| Immunohistochemistry analysis of paraffin embedded lung of mouse inflammatory model induced by LPS(6h) using Myeloperoxidase (GB15224) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat spleen using Myeloperoxidase (GB15224) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
