Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Monoclonal |
Gene Name: | Myeloperoxidase |
Synonyms: | MPO, myeloperoxidase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MPO |
Uniprot ID: | P11247 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Lysosome |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | Inflammatory model induced by lps(24h) lung, lung injury, |
Background
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Images
IHC analysis of Myeloperoxidase(GB150006). | |
IHC analysis of Myeloperoxidase(GB150006). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |