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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Myt1 rabbit polyclonal antibody |
Gene Name: | Myelin transcription factor 1 |
Synonyms: | MYT 1,Myt1, Myt 1, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A, ZC2H2C1, Myelin transcription factor 1, Proteolipid protein-binding protein |
Immunogen: | Recombinant protein corresponding to Mouse Myt1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 124 kDa |
Observed MW. | 124 kDa |
Uniprot ID: | Q01538, Q8CFC2 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, U87, U251, SH-SY5Y |
Background
Myelin transcription factor 1 is a protein encoded by the MYT1 gene. Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. Myt1 binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.
Images
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Western blot analysis of Myt1 (GB11854) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
