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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NET1 rabbit polyclonal |
Gene Name: | Neuroepithelial cell-transforming gene 1 protein |
Synonyms: | Net1, NET1, ARHGEF8, NET1A, Neuroepithelial cell transforming 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NET1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 200-1: 1000 | hippocampus, cerebellum, corpus striatum |
IF | Mouse, Rat | 1: 100-1: 250 | hippocampus, cerebellum, corpus striatum |
Background
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse hippocampus using NET1 (GB11758) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using NET1 (GB11758) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded Rat corpus striatum using NET1 (GB11758) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
