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Anti-NF-kB p65 Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Transcription factor p65 |
Synonyms: | RELA, NFKB3, p65, RELA proto-oncogene,NF-kB subunit |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human NF-κB p65 around the phosphorylation site of Serine 536 |
Uniprot ID: | Q04206 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 65 kDa / 65 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | HeLa, HepG2, A549 |
Background
Nuclear factor k B (NF-kB) is a sequence-specific DNA-binding protein complex which regulates the expression of viral genomes, including the human immunodeficiency virus, and a variety of cellular genes, particularly those involved in immune and inflammatory responses. The p65 subunit is a major component of NF-kB complexes and is responsible for trans-activation. NF-kB heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kB p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression.
Images
| Western blot analysis of NF-κB p65 (GB12142) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
