Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NMDAR2B rabbit polyclonal antibody |
Gene Name: | Glutamate receptor ionotropic, NMDA 2B |
Synonyms: | GRIN2B, GluN2B, MRD6, NMDAR2B, NR2B, hNR3, EIEE27 |
Immunogen: | Recombinant protein corresponding to Mouse NMDAR2B |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q01097, Q00960 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:400-1:1600 | brain |
Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. The NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heterotetramers composed of two molecules of the key receptor subunit NMDAR1 (GRIN1) and two drawn from one or more of the four NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
Images
Immunohistochemistry of paraffin embedded mouse brain using NMDAR2B (GB11381) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using NMDAR2B (GB11381) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using NMDAR2B (GB11381) at dilution of 1:400 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using NMDAR2B (GB11381) at dilution of 1:400 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |