Reactivity: | M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NPY1R rabbit polyclonal |
Gene Name: | Neuropeptide Y receptor type 1 |
Synonyms: | NPY1-R, Npy1r, NPYR, NPYY1, Neuropeptide Y receptor Y1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NPY1R |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 800-1: 1600 | spinal cord |
Background
This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.
Images
Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using NPY1R (GB113733) at dilution of 1: 1600 | |
Immunohistochemistry analysis of paraffin-embedded rat spinal cord using NPY1R (GB113733) at dilution of 1: 1600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |