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Anti-NR2E1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nuclear receptor subfamily 2 group E member 1 |
Synonyms: | TLL, TLX, XTLL |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NR2E1 |
Uniprot ID: | Q64104 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 43 kDa / 45-48 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | liver |
Background
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). Regulates cell cycle progression in neural stem cells of rhe developing brain. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells.
Images
| Western blot analysis of NR2E1 (GB114350) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
