Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NSUN2/SAKI rabbit polyclonal antibody |
Gene Name: | RNA cytosine C(5)-methyltransferase NSUN2 |
Synonyms: | Myc-induced SUN domain-containing protein, Misu, NOL1/NOP2/Sun domain family member 2, Nsun2, mRNA cytosine C(5)-methyltransferase, tRNA cytosine C(5)-methyltransferase |
Immunogen: | Recombinant protein corresponding to Mouse NSUN2/SAKI |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 85 kDa |
Observed MW. | 85 kDa |
Uniprot ID: | Q1HFZ0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, heart |
Background
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation.
Images
Western blot analysis of NSUN2 (GB112498) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |