Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NUDT11 rabbit polyclonal antibody |
Gene Name: | Diphosphoinositol polyphosphate phosphohydrolase 3-beta |
Synonyms: | DIPP-3-beta, DIPP3-beta, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta, Diadenosine hexaphosphate hydrolase (AMP-forming), Nudix motif 11, Nudt11, Dipp3b, MNCb-1696, Nucleoside diphosphate-linked moiety X motif 11 |
Immunogen: | Recombinant protein corresponding to Mouse NUDT11 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 19 kDa |
Observed MW. | 19 kDa |
Uniprot ID: | Q96G61, P0C028 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 300-1: 600 | kidney, testis, brain |
Background
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate; however, the relevance of such activity in vivo remains unclear.
Images
Western blot analysis of NUDT11 (GB112456) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |