Reactivity: | H,M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Nucleoporin p62/NUP62 rabbit polyclonal antibody |
Gene Name: | Nuclear pore glycoprotein p62 |
Synonyms: | 62 kDa nucleoporin, Nucleoporin Nup62, Nup62, IBSN, p62, SNDI |
Immunogen: | Recombinant protein corresponding to Mouse Nucleoporin p62 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 53 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | Q63850, P17955 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, colon, liver |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | brain, rectum |
Background
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.
Images
Western blot analysis of Nup62 (GB111998) at dilution of 1: 500 | |
Immunohistochemistry of paraffin embedded mouse rectum using Nup62 (GB111998) at dilution of 1: 650 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using Nup62 (GB111998) at dilution of 1: 650 (250x lens) | |
Immunofluorescence of paraffin embedded mouse brain using Nup62 (GB111998) at dilution of 1: 650 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |