Your shopping cart is empty!
Anti-Nav1.6/SCN8A Rabbit pAb (100 μl)
| Reactivity: | M & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Nav1.6/SCN8A rabbit polyclonal |
Gene Name: | Sodium channel protein type 8 subunit alpha |
Synonyms: | CerIII, CIAT, EIEE13, MED, NaCh6, Nav 1.6, Motor endplate disease, peripheral nerve protein type 4, PN4, SCN8A, Sodium channel protein type 8 alpha subunitVoltage gated sodium channel subunit alpha Nav1.6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Nav1.6/SCN8A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 225 kDa |
Observed MW. | 225 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 300-1: 600 | hypophysis, spinal cord |
IHC | Mouse, Rat | 1: 600-1: 1200 | hippocampus, brain |
Background
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
Images
| Western blot analysis of SCN8A (GB113741) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse hippocampus using SCN8A (GB113741) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using SCN8A (GB113741) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
