Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Nestin |
Synonyms: | NES, Nbla00170, nestin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Nestin |
Uniprot ID: | P48681 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, intermediate filament cytoskeleton |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | glioblastoma multiforme, kidney |
Background
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Images
IHC analysis of Nestin(GB115685). | |
IHC analysis of Nestin(GB115685). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |