Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Neurokinin A rabbit polyclonal antibody |
Gene Name: | Protachykinin-1 |
Synonyms: | PPT, Tac1, Nka, Nkna, Tac2, Hs.2563, Neuromedin L, NK2, PPT, Protachykinin 1, Substance K Neuropeptide K, Substance P, tachykinin, precursor 1 |
Immunogen: | Recombinant protein corresponding to Mouse Neurokinin A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P41539, P06767 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain |
Background
Achykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.TAC1 is an abbreviation for protachykinin 1, a protein that is encoded by the TAC1 gene, which is responsible for 4 products of the tachykinin peptide hormone family: substance P, neurokinin A, and the related peptides, neuropeptideK and neuropeptide . Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Images
Immunohistochemistry of paraffin embedded mouse brain using Neurokinin-A (GB111349) at dilution of 1:1100 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using Neurokinin-A (GB111349) at dilution of 1:1100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |