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Anti-OB Cadherin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OB Cadherin rabbit polyclonal antibody |
Gene Name: | Cadherin-11 |
Synonyms: | OSF-4, Cdh11, Cad-11, Osteoblast cadherin, OB-cadherin |
Immunogen: | Recombinant protein corresponding to Mouse OB Cadherin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 88 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | P55287, P55288 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, uterus |
Background
This gene encodes a type II classical cadherin from the cadherin super family, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-11 (OB-Cadherin) is a marker of the loosely connected and migratory cellular elements of the mesenchyme. Expression of this particular cadherin in osteoblastic cell lines, and its up regulation during differentiation, suggests a specific function in bone development and maintenance. Recently, Cadherin-11 mRNA and protein were found to be expressed in most invasive breast cancer cell lines tested but not in non-invasive cell lines, suggesting that Cadherin-11 may be a marker for aggressive, invasive tumor subsets.
Images
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Western blot analysis of OB-Cadherin (GB111278) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
