Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Deubiquitinase OTUD6B |
Synonyms: | CGI 77, DUBA 5, DUBA5, OTU domain containing 6B, OTUD6B |
Immunogen: | Recombinant protein corresponding to Mouse OTUD6B |
Uniprot ID: | Q8K2H2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 34 kDa / 37 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 3000 | heart |
Background
Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1. May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation. May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation. May also play a role in proteasome assembly and function.
Images
Western blot analysis of OTUD6B (GB115381) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |