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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Olig2 rabbit polyclonal antibody |
Gene Name: | Oligodendrocyte transcription factor 2 |
Synonyms: | Olig2, OLIG2, BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19, oligodendrocyte lineage transcription factor 2, oligodendrocyte transcription factor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Olig2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 32 kDa |
Observed MW. | 33 kDa |
Uniprot ID: | Q13516, Q9EQW6 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, cerebellum |
Background
Oligodendrocyte transcription factor (OLIG2) is a basic helix-loop-helix (bHLH) transcription factor encoded by the Olig2 gene. It is one of the three members of the bHLH family. The other two members are OLIG1 and OLIG3. The expression of OLIG2 is mostly restricted in central nervous system, where it acts as both an anti-neurigenic and a neurigenic factor at different stages of development. OLIG2 is well known for determining motor neuron and oligodendrocyte differentiation, as well as its role in sustaining replication in early development. It is mainly involved in diseases such as brain tumor and Down syndrome.
Images
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Western blot analysis of Olig2 (GB11766) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
