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| Reactivity: | R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | P2X3 rabbit polyclonal antibody |
Gene Name: | P2X purinoceptor 3 |
Synonyms: | P2RX3, P2X3, purinergic receptor P2X 3, ATP receptor, P2X purinoceptor 3, Purinergic receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse P2X3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | Q3UR32, P49654, P56373 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | brain, lung, small intestine, spleen |
Background
P2X purinoceptor 3 is a protein that in humans is encoded by the P2RX3 gene.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes, platelet aggregation, macrophage activation, apoptosis and neuronal–glial interactions.
Images
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Immunohistochemistry of paraffin embedded mouse lung using P2X3 (GB11348) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using P2X3 (GB11348) at dilution of 1:1500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat lung using P2X3 (GB11348) at dilution of 1:1500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat spleen using P2X3 (GB11348) at dilution of 1:1500 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using P2X3 (GB11348) at dilution of 1:1000 (400x lens) |
|
Immunofluorescence of paraffin embedded rat small intestine using P2X3 (GB11348) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
