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Anti-P2X3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | P2X3 rabbit polyclonal antibody |
Gene Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor, P2RX3, P2X purinoceptor 3, P2X3, Purinergic receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse P2X3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44/66 kDa |
Observed MW. | 44/66 kDa |
Uniprot ID: | Q3UR32, P49654, P56373 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | stomach, kidney, brain |
Background
P2X purinoceptor 3 is a protein that in humans is encoded by the P2RX3 gene.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes, platelet aggregation, macrophage activation, apoptosis and neuronal–glial interactions. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Images
| Western blot analysis of P2X3 (GB11348-1) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
