Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PACAP-38 rabbit polyclonal antibody |
Gene Name: | Pituitary adenylate cyclase-activating polypeptide |
Synonyms: | Pituitary adenylate cyclase-activating polypeptide 27, Adcyap1, Pacap, Pituitary adenylate cyclase-activating polypeptide 38, PACAP-38, PACAP-related peptide, PRP-48, PACAP27 |
Immunogen: | Recombinant protein corresponding to Mouse PACAP-38 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | O70176, P13589 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 300-1: 600 | brain |
Background
This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants.
Images
Immunohistochemistry of paraffin embedded mouse brain using ADCYAP1 (GB112282) at dilution of 1:300 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using ADCYAP1 (GB112282) at dilution of 1:300 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |