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Anti-PACSIN3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PACSIN3 rabbit polyclonal antibody |
Gene Name: | Protein kinase C and casein kinase II substrate protein 3 |
Synonyms: | Pacsin3, Endophilin 1, SDPIII, syndapin III, SH3 domain-containing protein 6511 |
Immunogen: | Recombinant protein corresponding to Human PACSIN3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | Q9UKS6, Q99JB8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, liver, lung |
Background
This gene plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity .
Images
| Western blot analysis of PACSIN3 (GB112369) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
