Reactivity: | M,R & R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PACT (PKR activating protein) / PRKRA rabbit polyclonal |
Gene Name: | Interferon-inducible double-stranded RNA-dependent protein kinase activator A |
Synonyms: | DYT16, HSD 14, HSD14, PACT, PKR associated protein X, PKR associating protein X, PRKRA, RAX |
Immunogen: | Recombinant protein corresponding to Mouse PRKRA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 34 kDa |
Observed MW. | 34 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | brain, testis, heart |
IHC | Rat | 1: 600-1: 1200 | brain, cerebellum, substantia nigra, frontal lobe |
Background
This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.
Images
Western blot analysis of PRKRA (GB113542) at dilution of 1: 1500 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using PRKRA (GB113542) at dilution of 1: 1200 | |
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using PRKRA (GB113542) at dilution of 1: 1200 | |
Immunohistochemistry analysis of paraffin-embedded rat frontal lobe using PRKRA (GB113542) at dilution of 1: 1200 | |
Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using PRKRA (GB113542) at dilution of 1: 1200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |