Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Peroxiredoxin-1 |
Synonyms: | Osteoblast-specific factor 3, Msp23, OSF-3, Thioredoxin peroxidase 2, Prdx1, Paga, Tdpx2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Peroxiredoxin 1 |
Uniprot ID: | P35700 |
Isotype: | IgG1,λ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 22 kDa / 22 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney, brain |
Background
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes. It is Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
Images
Western blot analysis of Peroxiredoxin1 (GB121151) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |