Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PAK2 rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein kinase PAK 2 |
Synonyms: | Gamma-PAK, p21-activated kinase 2, PAK-2, Pak2, C-t-PAK2, CB422, PAK-2p34, p27, p34, PAKgamma |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PAK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 58 kDa |
Observed MW. | 58 kDa |
Uniprot ID: | Q13177, Q8CIN4, Q64303 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, ovary |
Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, PAK2 also interacts with and is activated by HIV1 Nef.
Images
 | Western blot analysis of PAKgamma (GB112217) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
