Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Poly(A) polymerase beta polymerase) |
Synonyms: | PAP beta, PAPT, TPAP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PAP-beta |
Uniprot ID: | Q9WVP6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 72 kDa / 57 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 800 | testis |
Background
RelevanceThe function of this protein remains unknown. This gene is a member of the myotubularin family and encodes a putative tyrosine phosphatase. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene, but the protein products of some of these variants are likely not viable, as they are nonsense-mediated mRNA decay (NMD) candidates.
Images
Western blot analysis of PAPOLB (GB114932) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |