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Anti-PCID2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | PCI domain-containing protein 2 |
Synonyms: | CSN12 like protein, F10, PCI domain containing 2, PCID2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PCID2 |
Uniprot ID: | Q8BFV2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 46 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | heart |
Background
Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation . As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
Images
| Western blot analysis of PCID2 (GB114743) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
