Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PCMT1 rabbit polyclonal |
Gene Name: | Protein-L-isoaspartate(D-aspartate) O-methyltransferase |
Synonyms: | PIMT, L-isoaspartyl protein carboxyl methyltransferase, Pcmt1, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase |
Immunogen: | Recombinant protein corresponding to Mouse PCMT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 25 kDa |
Observed MW. | 25 kDa |
Uniprot ID: | P22061, P23506, P22062 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin, skeletal muscle, testis |
Background
The PCMT1 catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.
Images
Western blot analysis of PCMT1 (GB111538) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |