Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PDGFR alpha rabbit polyclonal antibody |
Gene Name: | Platelet-derived growth factor receptor alpha |
Synonyms: | PDGF-R-alpha, PDGFR alpha, CD140a, Pdgfra, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor |
Immunogen: | Recombinant protein corresponding to Mouse PDGFR alpha |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 123 kDa |
Observed MW. | 190 kDa |
Uniprot ID: | P26618, P20786 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, embryo |
Background
Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival and chemotaxis. Mutations in PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Images
Western blot analysis of PDGF alpha (GB111342) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |