Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PDK2 rabbit polyclonal antibody |
Gene Name: | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial |
Synonyms: | Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, Pdk2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID: | Q9JK42, Q64536 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, skeletal muscle, brain, cerebellum |
Background
PDK2([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial) is also named as PDHK2 and belongs to the PDK/BCKDK protein kinase family. PDK2 plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. PDK2 is also involved in the regulation of cell proliferation and in resistance to apoptosis under oxidative stress. This protein has 2 isoforms produced by alternative splicing.
Images
Western blot analysis of PDK2 (GB111934) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |