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Anti-PDLIM3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | PDZ and LIM domain protein 3 |
Synonyms: | Actinin associated LIM protein, ALP, PDLIM3, PDZ and LIM domain 3, Alpha-actinin-2-associated LIM protein |
Immunogen: | Recombinant protein corresponding to Mouse ALP |
Uniprot ID: | O70209 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 34 kDa / 34 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 1000-1: 2000 | lung |
Background
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
Images
 | Western blot analysis of PDLIM3 (GB113300) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
