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Anti-PDRG1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PDRG1 rabbit polyclonal antibody |
Gene Name: | p53 and DNA damage-regulated protein 1 |
Synonyms: | Pdrg1, Pdrg, C20orf126, p53 and DNA damage regulated 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDRG1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q9NUG6, P59048 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 200-1: 900 | esophagus, esophagus cancer, kidney, lung cancer, testis |
Background
PDRG1 codes for a novel protein called p53 and DNA damage-regulated protein 1. Human PDRG1 is predominantly expressed in normal testis and its expression can be induced by UV irradiation and be repressed by p53. Recently, PDRG1 was identified as a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress. Its expression was upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to normal tissues, suggesting its being a novel tumor marker that could play a role in cancer development and/or progression.
Images
| Immunohistochemistry of paraffin embedded human esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens) |
| Immunohistochemistry of paraffin embedded human lung cancer using PDRG1 (GB111733) at dilution of 1:300 (200x lens) |
| Immunohistochemistry of paraffin embedded human esophagus cancer using PDRG1 (GB111733) at dilution of 1:300 (300x lens) |
| Immunohistochemistry of paraffin embedded mouse esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens) |
| Immunohistochemistry of paraffin embedded rat esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens) |
| Immunofluorescence of paraffin embedded human lung cancer using PDRG1 (GB111733) at dilution of 1:300 (200x lens) |
| Immunofluorescence of paraffin embedded rat testis using PDRG1 (GB111733) at dilution of 1:250 (300x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using PDRG1 (GB111733) at dilution of 1:250 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
