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Anti-PDZD3 Rabbit pAb (100 μl)
| Reactivity: | R & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF4 |
Synonyms: | IKEPP, NaPi Cap2, NHERF 4, NHERF4, PDZ domain containing 3, PDZK2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDZD3 |
Uniprot ID: | Q99MJ6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Cytoplasm |
Predicted MW. / Observed MW. | 54 kDa / 57 kDa |
Product Usage Information
WB | Rat | 1: 1000-1: 2000 | kidney, testis |
IHC/IF | Mouse | 1: 500-1: 2000 | colon, spleen |
Background
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation (By similarity). Stimulates SLC9A3 activity in the presence of elevated calcium ions (By similarity).
Images
| Western blot analysis of PDZD3 (GB115087) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded mouse colon using PDZD3 (GB115087) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded mouse spleen using PDZD3 (GB115087) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
