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Anti-PDZK1 Rabbit pAb (100 μl)
| Reactivity: | M & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PDZK1 rabbit polyclonal antibody |
Gene Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 |
Synonyms: | CAP70, CLAMP, NaPi Cap1, NHERF 3, NHERF3, PDZ domain containing 1, PDZD1, PDZK1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDZK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 56 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9JIL4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 1000-1: 3000 | kidney, liver |
IHC/IF | Mouse | 1: 500-1: 1000 | small intestine, kidney |
Background
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1.
Images
| Western blot analysis of PDZK1 (GB113914) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded embedded mouse small intestine using PDZK1 (GB113914) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse kidney using PDZK1 (GB113914) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
