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| Reactivity: | M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PEX3 rabbit polyclonal antibody |
Gene Name: | Peroxisomal biogenesis factor 3 |
Synonyms: | Peroxin-3, Peroxisomal assembly protein PEX3, Pex3, TRG18 |
Immunogen: | Recombinant protein corresponding to Mouse PEX3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Peroxisome |
Predicted MW. | 42 kDa |
Observed MW. | 42 kDa |
Uniprot ID: | Q9QXY9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | kidney, liver |
IHC/IF | Human, Mouse, Rat | 1: 650-1: 1300 | kidney, liver, liver cancer |
Background
Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that anchored in the peroxisomal membrane and essential for peroxisome biogenesis and integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.
Images
 | Western blot analysis of Pex3 (GB112263) at dilution of 1: 500 |
 | Immunofluorescence of paraffin embedded human liver cancer using pex3 (GB112263) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse kidney using pex3 (GB112263) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse liver using pex3 (GB112263) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded rat kidney using pex3 (GB112263) at dilution of 1: 650 (350x lens) |
 | Immunofluorescence of paraffin embedded rat liver using pex3 (GB112263) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
