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| Reactivity: | H & H,M,R & H,M,R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PGD rabbit polyclonal |
Gene Name: | 6-phosphogluconate dehydrogenase, decarboxylating |
Synonyms: | PGD, PGDH, 6PGD, Phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase |
Immunogen: | Recombinant protein corresponding to Mouse PGD |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 53 kDa |
Observed MW. | 53 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HeLa, A549 |
IHC | Human, Mouse, Rat | 1: 900-1: 1800 | breast cancer, colon cancer, lung, brain, testis |
IF | Human, Mouse, Rat | 1: 900-1: 1800 | esophageal cancer, breast, brain, lung |
Background
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
Images
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Western blot analysis of PGD (GB111403) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: A549 cell lysate |
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Immunohistochemistry analysis of paraffin-embedded human breast cancer using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using PGD (GB111403) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded rat testis using PGD (GB111403) at dilution of 1: 900 |
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Immunofluorescent analysis of paraformaldehyde-fixed human esophageal cancer using PGD (GB111403) at dilution of 1: 900 |
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Immunofluorescent analysis of paraformaldehyde-fixed human breast using PGD (GB111403) at dilution of 1: 900 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using PGD (GB111403) at dilution of 1: 900 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using PGD (GB111403) at dilution of 1: 900 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
