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Anti-PI 3 Kinase p85 alpha Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PI 3 Kinase p85 alpha rabbit polyclonal |
Gene Name: | Phosphatidylinositol 3-kinase regulatory subunit alpha |
Synonyms: | PIK3R1, AGM7, GRB1, IMD36, P85, P85-ALPHA, Phosphoinositide-3-kinase regulatory subunit 1, PI 3 Kinase p85 alpha |
Immunogen: | Recombinant protein corresponding to Human PI 3 Kinase p85 alpha |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | cytoplasm |
Uniprot ID: | P26450, Q63787 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Mouse, Rat | 1: 2000-1: 4000 | brain |
ICC/IF | Human | 1: 500-1: 1000 | MCF7 |
Background
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse brain using PI 3 Kinase p85 alpha (GB11526) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using PI 3 Kinase p85 alpha (GB11526) at dilution of 1: 3000 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed MCF7 cells using PI 3 Kinase p85 alpha (GB11526) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
