Reactivity: | H & H,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PI3 Kinase p110 beta rabbit polyclonal antibody |
Gene Name: | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
Synonyms: | PI3-kinase subunit beta, PI3K-beta, PI3Kbeta, PtdIns-3-kinase subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, Pik3cb, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta |
Immunogen: | Recombinant protein corresponding to Mouse PI3 Kinase p110 beta |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 122 kDa |
Observed MW. | 122 kDa |
Uniprot ID: | P42338 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 250-1: 500 | HeLa, HepG2, A-431, K562 |
IHC/IF | Human, Rat | 1: 650-1: 1300 | hippocampus, renal cancer |
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection.
Images
Western blot analysis of PIK3CB (GB112375) at dilution of 1: 250 | |
Immunofluorescence analysis of paraffin embedded human renal cancer using PIK3CB (GB112375) at dilution of 1: 650 | |
Immunofluorescence analysis of paraffin embedded rat hippocampus using PIK3CB (GB112375) at dilution of 1: 650 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |