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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Quinone oxidoreductase PIG3 |
Synonyms: | Tumor protein p53-inducible protein 3, p53-induced gene 3 protein, TP53I3, PIG3 |
Immunogen: | Recombinant protein corresponding to Human PIG3 |
Uniprot ID: | Q53FA7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 36 kDa / 36 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HeLa, HepG2, MCF7, A549, 293T |
Background
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence.
Images
| Western blot analysis of PIG3 (GB111837) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
